Paradigm-shifting, physician-formulated innovations for gastrointestinal health.


ColonaryConcepts begins phase IIb trial of novel colonoscopy prep kit

Published in: Beckers GI & Endoscopy   Author: Eric Oliver

ColonaryConcepts, a device company, began a phase IIb trial of its colonoscopy preparation kit, EC Prep. Here's what you should know... Read More

ColonaryConcepts Sells Its Novel Colonoscopy Preparation Assets to a GI-Focused Specialty Pharma Company

Published in: Business Wire   Author: Joan E. Kureczka

ColonaryConcepts, LLC today announced the sale of its proprietary colonoscopy preparation assets to an undisclosed specialty pharmaceutical company that specializes in gastrointestinal health. The acquirer has secured worldwide rights to the unique colon prep technology, which integrates active ingredients into nutritionally balanced bars and beverages, with a goal of improving patient experience... Read More

VIDEO: Edible colon prep advances to phase 2b development

Published in: Healio

In this exclusive video from the World Congress of Gastroenterology at ACG 2017, Corey A. Siegel, MD, MS, associate professor of medicine and director of the Inflammatory Bowel Disease Center at Dartmouth-Hitchcock Medical Center in Lebanon, New Hampshire, discusses the next steps for development of an edible colon prep product for colonoscopy... Read More


If you’ve avoided colonoscopies because of the icky prep, help may be on the way

Published in: Washington Post   Author: Marlene Cimons

In a sense, children have had it better than grown-ups when it comes to patient-friendly care. They get to take flavored medications and at least one vaccine (oral polio) that is needle-free, with more probably on the way. Moreover, kids probably also still get the occasional lollipop (or stickers) for putting up with something that hurts... Read More

Colonoscopy prep may be getting less horrible

Published in: New York Daily News   Author: JOE DZIEMIANOWICZ

The worst thing about having a colonoscopy isn’t when you’re sedated and your doc scopes you where the sun don’t shine. It’s the prep, when you have to drink a gross laxative — and lots of it — to evacuate your plumbing for a clear reading. So gross. I’ve been there, so I appreciate efforts to build a better bowel cleaner. ... Read More

Novel Colonoscopy Prep Is Poised to Improve Screening Rates for Colon Cancer

Published in: Oncology Nurse Advisor   Author: Jason Hoffman, PharmD, RPh

Edible colon preparation (ECP) was found to be at least as effective and safe as currently available colonoscopy preparation formulations, and it was preferred with high satisfaction, according to study results presented at the American College of Gastroenterology 2016 Annual Scientific Meeting... Read More

RIP for the dreaded colonoscopy drink?

Published in: Fox News   Author: CNN Wire

To clear the colon and rectum for doctors to examine them for early signs of cancer, patients must guzzle a gargantuan amount of a salty, repulsive-tasting drink and laxative. While there are many different brands of this drink available, most of them have the same “ick” factor... Read More

RIP for the dreaded colonoscopy drink?

Published in: CNN   Author: Jacqueline Howard

When it comes to undergoing a colonoscopy, a screening test for colon cancer, many patients agree that the preparation is the worst part... Read More

ColonaryConcepts Initiates Phase 1 Study of New Approach to Treating Chronic Constipation

Published in: Business Wire   Author: Joan E. Kureczka

Edible bar-based formulation of PEG-3350 extends company’s work in developing patient-friendly colonoscopy prep to new indication... Read More

Drs. Corey Siegel, Joshua Korzenik develop new bar & beverage line for colonoscopy prep — 6 things to know

Published in: Becker's   Author: Allison Sobczak

Corey A. Siegel, MD, and Joshua R. Korzenik, MD, have developed a new bar and beverage line to help ease the colonoscopy prep process for patients, according to the Boston Business Journal. Here are six things to know... Read More

PEG 3350-containing bars, beverages an effective new approach to bowel prep for colonoscopy

Published in: Healio

The randomized, colonoscopist-blinded trial ended after 65 patients completed their colonoscopy, and more than 90% of those who consumed the novel ColonaryConcepts bowel prep regimen 24 hours before colonoscopy had ‘excellent’ or ‘good’ endoscopic visibility. Patients also reported high satisfaction, and no serious adverse events occurred... Read More

ColonaryConcepts Successfully Completes Phase 2 Study for a New Approach to Colonoscopy Prep for Colorectal Cancer Screening

Published in: Business Wire   Author: Joan E. Kureczka

ColonaryConcepts, LLC (CC) today announced positive topline results from a randomized, colonoscopist-blinded Phase 2 clinical study of the company’s novel investigational colonoscopy prep kit. The kit, to be available by prescription, is comprised of nutritionally balanced bars and beverages incorporating the standard purgative active ingredient, PEG 3350, which a patient consumes during the 24 hours prior to colonoscopy. Results of the study, ended after 65 patients completed a colonoscopy, showed successful colon cleansing (i.e., endoscopic visibility) in that over 90% of patients using the lead formulation had ‘excellent’ or ‘good’ rated colonoscopies. At the same time, participants reported high satisfaction with the CC kit and experienced no serious adverse events... Read More

Newton startup seeks to purge the unpleasantness from colonoscopy prep

Published in: Boston Business Journal   Author: Jessica Bartlett

When Dr. Corey Siegel was doing his gastroenterology fellowship at Massachusetts General Hospital, he spotted a troubling trend: Patients were avoiding colonoscopies because the preparation ahead of the procedure was so grueling. Siegel, who now works at Dartmouth-Hitchcock Medical Center, and his MGH mentor, Dr. Joshua Korzenik, who is now director of Brigham and Women’s Hospital Crohn’s and Colitis Center, have since embarked on developing a new bar and beverage line to help people prep for colonoscopies. The goal, he says, is to provide a more palatable alternative to the salty, sludgy liquid patients must imbibe ahead of the procedure... Read More

Purgative Meals for Colonoscopy Prep

Published in: Today's Geriatric Medicine   Author: Jamie Santa Cruz

Patients routinely complain that bowel preparation prior to a colonoscopy is a substantial turnoff, but a new alternative to traditional preparation methods has emerged on the horizon. Researchers from... Read More

ColonaryConcepts Announces First Patient Enrolled in Landmark Gastroenterologist-Designed Colon-Prep Phase 2 Study

Published in: Digital Journal   Author: MarketWired

ColonaryConcepts, LLC, a biotechnology company focused on breakthrough technology platforms that promote gastrointestinal health, announced the first patient enrolled in the landmark gastroenterologist-designed Colon Prep Phase 2 clinical trial... Read More

DDW: Scheduled for a colonoscopy? Pass the pretzels!

Published in: The Oncology Report   Author: PATRICE WENDLING, Oncology Practice Digital Network

A novel, edible colon preparation could make obsolete the fasting and large volume of salty liquid cleansing that keep many a patient from completing their colonoscopies. A pilot study showed that all 10 patients who ate a series of nutritionally balanced meals, drinks, and snacks such as pretzels and pudding had a successful colon cleansing according to the endoscopist at the time of the procedure, Dr. L. Campbell Levy of Dartmouth-Hitchcock Medical Center in Lebanon, N.H., reported at the annual Digestive Disease Week... Read More


You may not have to drink that nasty liquid before your colonoscopy

Published in: Washington Post   Author: Lenny Bernstein DC

There is general agreement that colonoscopies save lives. About 140,000 people will come down with colon or rectal cancers this year, according to the American Cancer Society, and about 50,000 people will die from those diseases. Yet an estimated 25 million people who should be screened don't have the procedure done... Read More


Bowel screening to become less of a pain in the backside

Published in: New Scientist   Author: Bob Roehr, Washington DC

Preparing for a colonoscopy isn't fun. Patients must fast and drink litres of fluid laced with foul-tasting chemicals to clean out their bowels. The good news is that a more friendly alternative is in the pipeline. Researchers developing the approach believe a single day of specially prepared foods, with the necessary laxatives and electrolytes incorporated into the preparation, can do the cleansing job just as well as the traditional, gruelling approach... Read More

Colonoscopy Prep Made Palatable

Published in: MD Magazine   Author: Glen Scott

Patients recommended for screening colonoscopy often resist because the bowel cleansing regimen is unpleasant. In an abstract presented May 17 at the 2015 Digestive Disease Week conference in Washington, DC, Campbell Levy, MD, of Dartmouth-Hitchcock Medical Center in Lebanon, NH, and colleagues at other institutions report on a novel edible product that achieves the desired results… Read More

Purgative Meals Touted as New Approach to Colonoscopy Prep

Published in: MedPage Today   Author: John Gever Managing Editor

Arguably the worst part of colonoscopies for patients was made a bit easier with a new approach to bowel cleansing, a researcher reported here. In a small pilot study, meals infused with the conventional laxative agent PEG-3350 along with sorbitol and ascorbic acid, which patients consumed the day before screening or surveillance colonoscopies, provided good-to-excellent bowel cleansing according to the endoscopists' standard grading, with good-to-excellent tolerability ratings from the patients as well, according to L. Campbell Levy, MD... Read More


ColonaryConcepts' colon preparation and ColonarySolutions' constipation products are in development, and are limited by Federal law to investigational use only. They have not been approved by the US Food and Drug Administration as safe or effective.